| CAS Number: | 20816-12-0 |
| MDL Number: | MFCD00011150 |
| Molecular Formula: | O4Os |
| Molecular Weight: | |
| Chemical Formula: | OsO4 |
| Color and Form: | colorless liq. |
| Note: |
Safety: Hazardous
| SECTION 1: Product Identification | |
|---|---|
| Chemical Name: | Osmium(VIII) oxide, 4% in water |
| Product Number: | 76-2952 |
| CAS Registry Number: | 20816-12-0 |
| Formula: | OsO4 |
| EINECS Number: | 244-058-7 |
| Chemical Family: | metal oxide |
| Synonym: | Osmic acid |
| SECTION 2: Composition and Information on Ingredients | ||||
|---|---|---|---|---|
| Ingredient | CAS Number | Percent | ACGIH (TWA) | OSHA (PEL) |
| Title compound | 20816-12-0 | 4 | 0.0002ppm (as OsO4) | 0.002mg/m3 (as Os) |
| water | 7732-18-5 | 96 | ||
| SECTION 3: Hazards Identification | |
|---|---|
| Emergency Overview: | Very toxic by inhalation, in contact with skin and if swallowed. Causes permanent damage to the eyes. Causes burns to skin and respiratory tract. |
| Primary Routes of Exposure: | Ingestion, inhalation, eyes, skin |
| Eye Contact: | Causes severe damage to eye tissue. Exposure to vapor can cause blindness. |
| Skin Contact: | Very toxic in contact with skin. Causes caustic burns of the skin. |
| Inhalation: | Very toxic by inhalation. Inhalation leads to structural and functional changes to the trachea. |
| Ingestion: | Very toxic if swallowed. |
| Acute Health Effects: | Very toxic by inhalation, in contact with skin and if swallowed. Damage to the eyes. Causes burns to skin, nose, mucous membranes and respiratory tract. |
| Chronic Health Effects: | No information available on long-term chronic effects. |
| NTP: | No |
| IARC: | No |
| OSHA: | No |
| SECTION 4: First Aid Measures | |
|---|---|
| Eye Exposure: | Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need assistance in keeping their eye lids open. Get immediate medical attention. |
| Skin Exposure: | Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if irritation persists. |
| Inhalation: | Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance. |
| Ingestion: | Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce vomiting only if directed by medical personnel. |
| SECTION 5: Fire Fighting Measures | |
|---|---|
| Flash Point: | none |
| Autoignition Temperature: | none |
| Explosion Limits: | none |
| Extinguishing Medium: | carbon dioxide, foam or dry powder |
| Special Fire Fighting Procedures: | If this product is involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure self- contained breathing apparatus and full protective clothing. |
| Hazardous Combustion and Decomposion Products: | If involved in a fire this material may emit irritating fumes. |
| Unusual Fire or Explosion Hazards: | No unusual fire or explosion hazards. |
| SECTION 6: Accidental Release Measures | |
|---|---|
| Spill and Leak Procedures: | If released outside an area of adequate ventilation, evacuate the area. Enter only if equipped with a self-contained breathing apparatus. Absorb liquid in vermiculite or other suitable adsorbent. |
| SECTION 7: Handling and Storage | |
|---|---|
| Handling and Storage: | Store in a tightly sealed container. Keep away from heat and moisture. Handle only in a efficient fume hood. |
| SECTION 8: Exposure Controls and Personal Protection | |
|---|---|
| Eye Protection: | Always wear approved safety glasses when handling a chemical substance in the laboratory. |
| Skin Protection: | Wear protective clothing and gloves. |
| Ventilation: | Adequate ventilation is essential. Vapor is extremely hazardous. Handle material only in an efficient fume hood. |
| Respirator: | If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator Protection Program to be in compliance with 29 CFR 1910.134. |
| Additional Protection: | No additional protection required. |
| SECTION 9: Physical and Chemical Properties | |
|---|---|
| Color and Form: | colorless liquid |
| Molecular Weight: | 254.20 |
| Melting Point: | no data |
| Boiling Point: | no data |
| Vapor Pressure: | no data |
| Specific Gravity: | no data |
| Odor: | none |
| Solubility in Water: | material is a water solution |
| SECTION 10: Stability and Reactivity | |
|---|---|
| Stability: | air and moisture-stable liquid |
| Hazardous Polymerization: | none |
| Conditions to Avoid: | Oxidizer. Avoid mixing or heating with combustible materials. |
| Incompatibility: | Reducing agents, alcohols, alkenes, chlorinated hydrocarbons |
| Decomposition Products: | osmium tetroxide vapors, osmium metal |
| SECTION 11: Toxicological Information | |
|---|---|
| RTECS Data: | For pure osmium tetroxide: Inhalation (human); TCLo: 133ug/m3. Inhalation (rat); LCLO: 40ppm/4H. Intraperitoneal (rat); LD50: 14100ug/m3. Oral (mouse): 162mg/kg. Inhalation (mouse); LCLo: 40ppm/4H. Intraperitoneal (mouse); LD50: 13500ug/m3. Inhalation (rabbit); LCLo: 1316mg/m3/30M. Intratesticular (rat); TDLo: 20336/ug/m3. Subcutaneous (mouse); TDLO: 20336ug/kg. Lacrymator. Damage to eyes. Inhalation leads to structural and functional changes to the trachea and bronchi. Paternal effects - testes, epididymis, genetic material. Inhalation can lead to coma in test animals. |
| Carcinogenic Effects: | No data available |
| Mutagenic Effects: | Suspected mutagen |
| Tetratogenic Effects: | No data available |
| SECTION 12: Ecological Information | |
|---|---|
| Ecological Information: | No information available |
| SECTION 13: Disposal Considerations | |
|---|---|
| Disposal: | Dispose of according to local, state and federal regulations. |
| SECTION 14: Transportation | |
|---|---|
| Shipping Name (CFR): | Osmium tetroxide |
| Hazard Class (CFR): | 6.1 |
| Additional Hazard Class (CFR): | NA |
| Packaging Group (CFR): | I |
| UN ID Number (CFR): | UN# 2471 |
| Shipping Name (IATA): | Osmium tetroxide |
| Hazard Class (IATA): | 6.1 |
| Additional Hazard Class (IATA): | NA |
| Packaging Group (IATA): | I |
| UN ID Number (IATA): | UN# 2471 |
| SECTION 15: Regulatory Information | |
|---|---|
| TSCA: | listed on the TSCA inventory |
| SARA (Title 313): | Repeortable under SARA 313. |
| Second Ingredient: | none |
| Third Ingredient: | none |
| SECTION 16: Other Information | |
|---|---|
| Disclaimer: | The information herein is believed to be accurate and reliable as of the date compiled. However, Strem Chemicals, Inc. makes no representation, warranty, or guarantee of any kind with respect to the information contained in this document or any use of the product based on this information. |
| Preparation Date: | 9/12/1999 |
| Revision Date: | 8/01/2011 |