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Strem Appointed World-Wide Distributor of Takasago’s Patented Catalysts

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Newburyport, MA, March 26, 2007-- Strem Chemicals, Inc, a manufacturer of specialty chemicals for research and development, is pleased to announced that it has signed an agreement that appoints it as the world-wide distributor of Takasago’s patented catalyst and ligand technologies. The portfolio covers several well known families of products, most notably the BINAP family and its next generation version, the SEGPHOS family.

The BINAP family was developed by the late Professor Takaya and Professor Noyori who received the Nobel prize in Chemistry in 2001 for his contributions in chiral catalyzed hydrogenation reactions employing BINAP catalysts and is a Takasago Board Member. The SEGPHOS family was developed by Takasago scientists led by Dr. Saito who now serves as Vice President of the Fine Chemicals Division. BINAP and SEGPHOS technologies have been used extensively for asymmetric hydrogenation of a wide variety of substrates on an industrial scale. BINAP hydrogenations can be replaced with SEGPHOS and SEGPHOS generally works better than BINAP.

“We are very pleased that Takasago has decided to make their catalysts and ligands available through Strem Chemicals. Our customers in the pharmaceutical industry will now be able to readily gain access to these technologies which we anticipate will facilitate their drug discovery and development efforts” said Dr. Ephraim S. Honig, C.O.O. at Strem.

Takasago’s broad range of technologies has not previously been available to the research market. “ Takasago decided to work with Strem because of its reputation as a high quality manufacturer and distributor of catalysts and ligands”, said Mr. Yutaka Okamura, US Director of Fine Chemicals for Takasago. “We have the largest patented ligand and application platforms that have already been proven at commercial scale. We decided the time was right to make these accessible through Strem”.

Strem will offer research quantities of Takasago’s catalysts and ligands. Larger quantities will continue to be available from Takasago. More information is available at www.strem.com .

About Strem Chemicals
Strem Chemicals, Inc., established in 1964, is a privately held manufacturer and marketer of specialty chemicals of high purity. Strem’s key products include catalysts, ligands, organometallics, metal carbonyls and nanomaterials. Its products are used for research and development and commercial scale applications, especially in the pharmaceutical, microelectronics, chemicals and petrochemicals industries. Strem Chemicals also provides custom synthesis, process development and cGMP manufacturing services. For more information visit www.strem.com.


About Takasago Fine Chemicals
Takasago was established in 1920 as a perfumery company. Our synthetic technology traces back to manufacture of Vanillin and Heliotropine in 1927. Ever since, many aroma chemicals have been produced. Our chiral technologies commenced with ℓ-Menthol synthesis by catalytic asymmetric isomerization using BINAP ligand, which was developed in collaboration with Professor Ryoji Noyori, who was awarded the Nobel Prize for Chemistry in 2001, and who is a Takasago board member. The technology expanded to asymmetric hydrogenation to produce various kinds of chiral compounds, such as flavors, fragrances, and agrochemical and pharmaceutical ingredients. Our current chiral output from the technology is approximately 3,000 tons annually.
Takasago Fine Chemicals Division was established about 20 years ago when Takasago developed the catalytic asymmetric synthesis technology using BINAP ligands. In Takasago, we refer to BINAP as the first generation ligand. Over time Takasago Fine Chemicals has discovered several generations of novel chiral ligands, as well as many catalysts. Although we still think BINAP is the most famous chiral ligand in the world, Takasago is now focusing on the next generation ligand, SEGPHOS.
For more information please contact below;
Yutaka Okamura, Director of Fine Chemicals Division, Takasago International Corporation, USA
Tel: 201-784-7299, Fax: 201-784-7277, E-mail: yokamura@takasago.com

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