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Strem and Provivi Sign Enzyme Distribution Agreement

Newburyport, MA and Santa Monica, CA (September 9, 2014) —The agreement grants Strem distribution rights for research quantities of Provivi’s carbene/nitrene transferase enzymes that will feature in the new C/N Transferase Screening Kit. These enzymes can efficiently activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids, respectively, through a mode of activation that has never been observed in nature. These intermediates can react with a variety of substrates such as olefins, N-H bonds, C-H bonds, and sulfides, offering great synthetic utility, as for example in the synthesis of chiral cyclopropanes and sulfimides.

The screening kit contains 32 enzymes that were engineered in the laboratory of Prof. Frances Arnold, at Caltech. Provivi obtained a worldwide exclusive license to this technology. The kit will be available through Strem so that researchers are able to quickly screen a small number of diverse biocatalysts to pick the best solution.

“We are pleased to announce this partnership with Strem, a global manufacturer and distributor of catalysts”, said Dr. Pedro Coelho, Chief Executive Officer, at Provivi. “Based on Strem’s established network of scientific customers, we are looking forward to giving them the opportunity to use our enzymes to develop highly efficient strategies for the synthesis of drugs, pesticides, and other fine chemicals.”

“Strem is happy to be working with Provivi, a new and innovative company in the field of Biocatalysis”, said Dr. Ephraim Honig, Chief Operating Officer at Strem. “The addition of the C/N Transferase Screening Kit will provide new pathways to the enantioselective synthesis of important functional groups extending the tools available to synthetic scientists.”

About Strem Chemicals
Strem Chemicals, Inc., established in 1964, is a privately held manufacturer and marketer of specialty chemicals of high purity. Strem’s key products include catalysts, ligands, organometallics, metal carbonyls and nanomaterials. Its products are used for research and development and commercial scale applications, especially in the pharmaceutical, microelectronics, chemicals and petrochemicals industries. Strem Chemicals also provides custom synthesis, process development and cGMP manufacturing services. For more information visit

About Provivi, Inc.
Provivi, Inc. develops high-performance, affordable biopesticides for agriculture, commercial, household, and public health pest management. Our products respect the environment, improve human health, and are inspired by chemical ecology and biosynthesis. For more information, see

About the Kit
The Kit (Strem Catalog No. 96-1580 Provivi Carbene/Nitrene Transferase Screening Kit) contains 32 Provivi enzymes.

Contacts: Strem Chemicals, Inc., Provivi, Inc.

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