Dirhodium tetracarboxylate complexes have been extensively studied over the past few decades. There has been an interest in respect to their applications in catalysis and in particular for a wider number of selective transformations such as intermolecular and intramolecular C-H insertion, cycloaddition and other organic reactions. Insertions of a carbene or nitrene into unactivated C–H bonds, promoted by donor/acceptor-substituted Rh carbenoid, have gained special attention.[1-2] Most of these catalysts are notable for their stereoselectivity as well as their stability when exposed to heat, moisture or ambient atmospheres.[3]
Strem offers dirhodium paddle-wheel structured chiral catalysts which were developed within the last few years. These products have opened up new possibilities for researchers. Rh2(R,S-PTAD)4 (45-2070: R-modification, 45-2071: S-modification) is useful for intermolecular cyclopropanation of olefins with R-aryl-R-diazo ketones, cyclopropanation reactions of diazo compounds with cyano group, asymmetric of diazo sulfonylamidines and other reactions. Catalysts Rh2(R-BTPCP)4 (45-2080: R-modification, 45-2081: S-modification) and Rh2(R-DOSP)4 (45-2100 R-modification, 45-2101 S-modification) are also used for enantioselective cyclopropanation as well as asymmetric synthesis.
Rh2(S-PTTL)4 (45-2105) is a recent addition to our catalog. This catalyst is not only applicable for customary dirhodium catalytic reactions, but also allows certain adducts to be extracted from the reaction mixture with a very high purity. This quality is what makes this catalyst interesting for biomedical applications.
In addition to chiral catalysts, Strem offers a classical halogen free dirhodium complex (45-0390) [Rh(OMe)(COD)]2 which can be used both as a catalyst and also for organometallic and nano preparations.
For more product details and references please see these products’ corresponding technical notes.
References:
Products mentioned in this blog and related products:
45-0390: Di-μ-methoxobis(1,5-cyclooctadiene)dirhodium(I), min. 98% [12148-72-0]
Please also see our Dirhodium Catalysts literature sheet for more technical details on these products.