| CAS Number: | 1303-28-2 |
| MDL Number: | MFCD00003434 |
| Molecular Formula: | As2O5 |
| Molecular Weight: | 229.79 |
| Chemical Formula: | As2O5 |
| Color and Form: | white pwdr. |
| Note: |
Stability: moisture sensitive
Safety: Hazardous
Physical Characteristics: melting point 315°C dec., density 4.32
| SECTION 1: Product Identification | |
|---|---|
| Chemical Name: | Arsenic (V) oxide (99.9+%-As) |
| Product Number: | 93-3304 |
| CAS Registry Number: | 1303-28-2 |
| Formula: | As2O5 |
| EINECS Number: | 215-116-9 |
| Chemical Family: | metal oxide |
| Synonym: | Arsenic acid anhydride, Diarsenic pentoxide |
| SECTION 2: Composition and Information on Ingredients | ||||
|---|---|---|---|---|
| Ingredient | CAS Number | Percent | ACGIH (TWA) | OSHA (PEL) |
| Title Compound | 1303-28-2 | 100 | 0.01mg/m3 (as As) | 0.01mg/m3 (as As) |
| SECTION 3: Hazards Identification | |
|---|---|
| Emergency Overview: | Very toxic if swallowed. Toxic by inhalation. May cause cancer and heritable genetic damage. Possible risk of impaired fertility. |
| Primary Routes of Exposure: | Contact with skin and eyes. Dust inhalation. |
| Eye Contact: | May cause mild to severe irritation of the eyes. |
| Skin Contact: | May cause irritation of the skin, ulceration, spotty pigmentation, dermatitis, and skin cancer. |
| Inhalation: | May be severely irritating to the nose, and respiratory tract. May induce perforation of the nasal septum and cause arsenic poisoning. |
| Ingestion: | Ingestion may lead to nausea, vomiting, bloody diarrhea, weakness, low blood pressure, shock, coma, and death. |
| Acute Health Effects: | May be irritating to skin, eyes and respiratory tract. Very toxic if swallowed. Causes garlic breath odor, nausea, vomiting, bloody diarrhea, weakness and coma. |
| Chronic Health Effects: | Prolonged exposure to arsenic compounds may cause loss of appetite, dermatitis, diarrhea, kidney and liver damage, nervous disorders, and cancer of the skin, lungs, and liver. |
| NTP: | Yes |
| IARC: | Yes |
| OSHA: | Yes |
| SECTION 4: First Aid Measures | |
|---|---|
| Eye Exposure: | Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need assistance in keeping their eye lids open. Get immediate medical attention. |
| Skin Exposure: | Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if irritation persists. |
| Inhalation: | Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance. |
| Ingestion: | Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce vomiting only if directed by medical personnel. |
| SECTION 5: Fire Fighting Measures | |
|---|---|
| Flash Point: | not applicable |
| Autoignition Temperature: | not applicable |
| Explosion Limits: | not applicable |
| Extinguishing Medium: | None. Material is non-flammable. |
| Special Fire Fighting Procedures: | If this product is involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure self-contained breathing apparatus. |
| Hazardous Combustion and Decomposion Products: | If involved in a fire, toxic fumes of arsenous oxide may be produced. |
| Unusual Fire or Explosion Hazards: | No unusual fire or explosion hazards. |
| SECTION 6: Accidental Release Measures | |
|---|---|
| Spill and Leak Procedures: | Small spills can be mixed with vermiculite or sodium carbonate and swept up. |
| SECTION 7: Handling and Storage | |
|---|---|
| Handling and Storage: | Store in a tightly sealed container. When handling, avoid forming airborne dust. Use good housekeeping practices to avoid contamination of work area. |
| SECTION 8: Exposure Controls and Personal Protection | |
|---|---|
| Eye Protection: | Always wear approved safety glasses when handling a chemical substance in the laboratory. |
| Skin Protection: | Wear appropriate chemical resistant gloves and protective clothing. |
| Ventilation: | Material may form a fine dust. If possible, handle the material in an efficient fume hood. |
| Respirator: | If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator Protection Program to be in compliance with 29 CFR 1910.134. |
| Additional Protection: | Contaminated clothing should be managed in a way to prevent secondary exposure to toxic dust |
| SECTION 9: Physical and Chemical Properties | |
|---|---|
| Color and Form: | white pwdr. |
| Molecular Weight: | 229.79 |
| Melting Point: | 315°C dec. |
| Boiling Point: | no data |
| Vapor Pressure: | not applicable |
| Specific Gravity: | 4.32 |
| Odor: | none |
| Solubility in Water: | 150g/100cc (16°C) |
| SECTION 10: Stability and Reactivity | |
|---|---|
| Stability: | moisture sensitive solid |
| Hazardous Polymerization: | no hazardous polymerization |
| Conditions to Avoid: | Nascent hydrogen or metal hydrides may produce highly toxic arsine gas. |
| Incompatibility: | active metals and strong bases |
| Decomposition Products: | none |
| SECTION 11: Toxicological Information | |
|---|---|
| RTECS Data: | Oral (rat); LD50: 8 mg/kg. Oral (mouse); LD50: 55 mg/kg. Subcutaneous (rabbit); LDLo: 12400 ug/kg. Intravenous (rabbit); LDLo: 6 mg/kg. Intratesticular (rat); TDLo: 4597 ug/kg. Subcutaneous (mouse); TDLo: 4597 ug/kg. Human Fibroblast; DNA inhibition: 100 umol/L. Human Leukocyte; Cytogenetic analysis: 1200 nmol/L. |
| Carcinogenic Effects: | Tumorigenic - Carcinogenic by RTECS criteria |
| Mutagenic Effects: | Mutagen |
| Tetratogenic Effects: | Reproductive Effector |
| SECTION 12: Ecological Information | |
|---|---|
| Ecological Information: | Avoid release to the environment. Very toxic to aquatic organisms. May cause long-term adverse effects in the environment. |
| SECTION 13: Disposal Considerations | |
|---|---|
| Disposal: | Dispose of according to local, state and federal regulations. |
| SECTION 14: Transportation | |
|---|---|
| Shipping Name (CFR): | Arsenic pentoxide |
| Hazard Class (CFR): | 6.1 |
| Additional Hazard Class (CFR): | NA |
| Packaging Group (CFR): | II |
| UN ID Number (CFR): | UN# 1559 |
| Shipping Name (IATA): | Arsenic pentoxide |
| Hazard Class (IATA): | 6.1 |
| Additional Hazard Class (IATA): | NA |
| Packaging Group (IATA): | II |
| UN ID Number (IATA): | UN# 1559 |
| SECTION 15: Regulatory Information | |
|---|---|
| TSCA: | Listed in the TSCA inventory. |
| SARA (Title 313): | Title compound: See Category Code N020 for reporting. |
| Second Ingredient: | none |
| Third Ingredient: | none |
| SECTION 16: Other Information | |
|---|---|
| Disclaimer: | The information herein is believed to be accurate and reliable as of the date compiled. However, Strem Chemicals, Inc. makes no representation, warranty, or guarantee of any kind with respect to the information contained in this document or any use of the product based on this information. |
| Preparation Date: | 3/20/2001 |
| Revision Date: | 8/02/2011 |